QUESTION:  
63% of all people agree that it could be a perfect day until this one thing happens and it would instantly ruin their good mood; what is it?

 
It has everything to do with work
It may have everything to do with work but you are not working when this happens 

ANSWER:
63% of all people agree that it could be a perfect day until their boss calls their phone.  63% of all people agree that call would instantly ruin their good mood. 
                    
Congratulations to Tom Ragan of Centerville, IN for being the first to answer the Impossible Question correctly!